For professionals dealing with individuals with these syndromes, the patient’s or client’s behavior can be puzzling. Inflexible patients can be very anxious, resistant to new ideas or procedures and argumentative. This does not represent oppositional behavior. Their concerns need to be understood and addressed before they will be more cooperative. Many patients will seem to overreact to situations that seem minor and to hold onto fixed ideas that are counter-productive. Transitions are difficult and previewing procedures step by step is very helpful. Often it is very helpful to encourage slow breathing or other self-calming techniques that lower immediate arousal, although this has to be done before the patient becomes agitated. Parents or the individuals themselves can explain prospective problems, which makes it possible to be proactive in helping. Sometimes, introducing these patients to new places, professionals and procedure prior to the actual start of services can facilitate a better experience for all involved.